2. Immunology/Inflammation Anti-infection
  3. Toll-like Receptor (TLR) Antibiotic
  4. FSL-1

FSL-1 是细菌衍生的一种 Toll 样受体 2/6 (TLR2/6) 激动剂，可增强对HSV-2感染的抵抗力。

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FSL-1 Chemical Structure

FSL-1 Chemical Structure

CAS No. : 322455-70-9

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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FSL-1 的其他形式现货产品:

Customer Review

Other Forms of FSL-1:

FSL-1 相关抗体

Top Publications Citing Use of Products

查看 Toll-like Receptor (TLR) 亚型特异性产品:

查看所有亚型
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

查看 Antibiotic 亚型特异性产品:

查看所有亚型
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1][2].

IC50 & Target[1][2]

TLR2

 

TLR6

 

体外研究
(In Vitro)

FSL-1 significantly reduces HSV-2 replication in vitro. FSL-1 reduces HSV-2 replication in human vaginal epithelial cells (EC)[1].
FSL-1 induces significant resistance to experimental genital HSV-2 infection through elaboration of a specific cytokine response profile[1].
FSL-1 enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signalling pathway[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

FSL-1 相关抗体:

Cell Viability Assay[1]

Cell Line: V11I, V12I or V19I immortalized human vaginal EC
Concentration: 6 μg or 0.1 μg
Incubation Time: Added at 24, 6 or just prior to HSV-2 inoculation (104pfu/well)
Result: The 6 μg does produced significant reductions when delivered at 24 or 6 h prior to HSV-2 inoculation. The 0.1 μg dose produced reduced HSV-2 replication at 24 or 6 h prior to viral challenge.
分子量

1666.16

Formula

C84H140N14O18S
CAS 号
非同位 CAS

Sequence

Ser-(2,3-Bispalmitoyloxypropyl)-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe
Sequence Shortening

S-(2,3-Bispalmitoyloxypropyl)-CGDPKHPKSF
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FSL-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FSL-1322455-70-9FSL1FSL 1Toll-like Receptor (TLR)AntibioticInhibitorinhibitorinhibit

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产品名称：
FSL-1
目录号：
HY-P2036
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