2. Gene
  3. PPID - peptidylprolyl isomerase D Gene

PPID - peptidylprolyl isomerase D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肽基脯氨酰异构酶 D

种属: Homo sapiens

同用名: CYPD; CYP-40

基因 ID: 5481 | 基因类型: protein coding

关于 PPID

Cytogenetic location: 4q32.1 Genomic coordinates (GRCh38): 4:158,709,127-158,723,396 (from NCBI)

This gene has 3 transcripts (splice variants), 243 orthologues and 22 paralogues. Ubiquitous expression in testis (RPKM 15.6), duodenum (RPKM 13.0) and 25 other tissues.

功能概要

该基因编码的蛋白质是肽基-脯氨酰顺反异构酶 (PPIase) 家族的成员。 PPIases 催化寡肽中脯氨酸亚胺肽键的顺反异构化，加速蛋白质的折叠。这种蛋白质已被证明具有 PPIase 活性，并且与其他家族成员相似，可以与免疫抑制剂环孢菌素 A 结合。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

PPID 基因产物(1)

mRNA Protein Name
NM_005038.3 NP_005029.1 peptidyl-prolyl cis-trans isomerase D

PPID 蛋白结构

Pro_isomerase

Pro_isomerase: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD (20 - 182)

TPR_7

TPR_7: Tetratricopeptide repeat (226 - 252)

TPR_11

TPR_11: TPR repeat (278 - 337)

  • 0
  • 100
  • 200
  • 300
  • 370 a.a.
蛋白主名 其他名称

peptidyl-prolyl cis-trans isomerase D

40 kDa peptidyl-prolyl cis-trans isomerase D

重组 PPID 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71224 PPID Protein, Human (His) Q08752 (M1-A370) ≥95%

关联疾病

疾病名称 别名
Anaplastic Large Cell Lymphoma

Alcl

Cd30 Positive Anaplastic Large Cell Lymphoma

Ki-1 Positive Anaplastic Large Cell Lymphoma

Primary Systemic Alcl

Sacl

Ki-1+ Anaplastic Large Cell Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10949 PPID Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PPID RGD RGD:1303174
Bos taurus PPID VGNC VGNC:33197
Canis familiaris PPID VGNC VGNC:44851
Felis catus PPID VGNC VGNC:79975
Mus musculus PPID MGD MGI:1914988
Others PPID NCBI
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