2. Epigenetics Metabolic Enzyme/Protease
  3. Small Interfering RNA (siRNA) Ser/Thr Protease
  4. Inclisiran sodium

Inclisiran sodium  (Synonyms: ALN-PCSsc sodium)

目录号: HY-132591A 纯度: 91.03%
COA 产品使用指南

摩尔计算器

Inclisiran sodium 是一种双链小干扰 RNA (siRNA) 分子，可抑制 PCSK-9 的转录。Inclisiran sodium 可用于高脂血症和心血管疾病 (CVD) 研究。

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RNA, (Am-sp-(2'-deoxy-2'-fluoro)C-sp-Am-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'- fluoro)A-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)C-Am-(2'-deoxy-2'-fluoro)AAm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)A-Gm-(2'-deoxy-2'-fluoro)G-Um-(2'-deoxy-2'-fluoro)C-Um-Am-Gm-sp-Am-sp-Am), complex with RNA (Cm-sp-Umsp -Am-Gm-Am-Cm-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Um-dT-UmUm-Gm-Cm-Um-Um-Um-Um-Gm-Um) 3'-[[(2S,4R)-1-[29-[[2-(acetylamino)-2- deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-βD-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-3-oxopropoxy]methyl]- 1,12,19,25-tetraoxo-16-oxa-13,20,24-triazanonacos-1-yl]-4-hydroxy-2- pyrrolidinyl]methyl hydrogen phosphate] (1:1), sodium salt

Inclisiran sodium Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥6240
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Inclisiran sodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Inclisiran sodium is a double-stranded small interfering RNA (siRNA) molecule that inhibits the transcription of PCSK-9. Inclisiran sodium can be used for hyperlipidemia and cardiovascular disease (CVD) research[1].

分子量

17306.68

Formula

C529H663F12N176Na44O316P43S6
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: 98.10%

COA (192 KB) RP-HPLC (237 KB)

产品使用指南 (1538 KB)
参考文献

Inclisiran sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

InclisiranALN-PCSscSmall Interfering RNA (siRNA)Ser/Thr ProteaseSerine proteasesSerine endopeptidasesThreonine proteasessiRNAhyperlipidemiacardiovasculardiseaseLDL-CPCSK-9Inhibitorinhibitorinhibit

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目录号：
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