CD300e 蛋白, Human (HEK293, Fc)

The CD300e protein may be an activating receptor, suggesting involvement in cell signaling and immune responses. CD300e interacts with TYROBP to regulate cellular activities and coordinate immune responses. CD300e Protein, Human (HEK293, Fc) is the recombinant human-derived CD300e protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD300e Protein, Human (HEK293, Fc) is 173 a.a., with molecular weight of 55-57 KDa.

CD300e 蛋白可能是一种激活受体，表明它参与细胞信号传导和免疫反应。通过与 TYROBP 相互作用，CD300e 可能在调节细胞活动和协调免疫反应中发挥作用。阐明受 CD300e 影响的特定配体和下游信号通路将有助于更深入地了解其在免疫调节中的功能意义。对涉及 CD300e 的分子相互作用和细胞环境及其与 TYROBP 的关联的进一步研究将为了解其作为免疫过程中激活受体的作用提供有价值的见解。

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion by human T cells. The ED₅₀ for this effect is 1.707 μg/mL. Corresponding to a specific activity is 585.823 U/mg.

• 
  Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion by human T cells. The ED₅₀ for this effect is 1.707 μg/mL. Corresponding to a specific activity is 585.823 U/mg.

Human

HEK293

C-hFc

Q496F6 (L18-H173)

342510  [NCBI]

LKGPGSVTGTAGDSLTVWCQYESMYKGYNKYWCRGQYDTSCESIVETKGEEKVERNGRVSIRDHPEALAFTVTMQNLNEDDAGSYWCKIQTVWVLDSWSRDPSDLVRVYVSPAITTPRRTTHPATPPIFLVVNPGRNLSTGEVLTQNSGFRLSSPH

Approximately 55-57 kDa due to the glycosylation.

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.