1. Apoptosis
  2. Apoptosis
  3. Visilizumab

Visilizumab  (Synonyms: Anti-Human CD3E Recombinant Antibody; HuM291)

目录号: HY-P99332 纯度: 98.43%
COA

Visilizumab (Anti-Human CD3E Recombinant Antibody) 是一种人源化低 Fc 受体结合抗 CD3 单克隆 IgG2 抗体。Visilizumab 可用于溃疡性结肠炎和克罗恩病的研究。

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Visilizumab Chemical Structure

Visilizumab Chemical Structure

CAS No. : 219716-33-3

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research[1].

同型

Human IgG2 kappa

推荐同型对照抗体
种属

Humanized

体外研究
(In Vitro)

Visilizumab 诱导固有层 T 细胞的剂量和时间依赖性细胞凋亡。Visilizumab 诱导固有层 T 细胞凋亡依赖于半胱天冬酶 3 和 8,而不是半胱天冬酶 9 的激活,并且不涉及 Fas/FasL 通路[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: Lamina propria T cells
Concentration: 1 ng/mL, 10 ng/mL, 100 ng/mL, 1000 ng/mL, 10000 ng/mL
Incubation Time: 2 hours, 4 hours, 20 hours, 24 hours, 48 hours
Result: Induced dose- and time-dependent apoptosis of lamina propria T cells.
Clinical Trial
CAS 号
Unlabeled Cas

性状

液体

颜色

Colorless to light yellow

中文名称

维西珠单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Visilizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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