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3-CPs  (Synonyms: 3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen)

目录号: HY-U00265
产品使用指南

3-CPs 是可以干扰抗体介导的细菌杀伤的血清型荚膜多糖。

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3-CPs Chemical Structure

3-CPs Chemical Structure

CAS No. : 20073-24-9

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  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing.

体外研究
(In Vitro)

3-CPs displays protective effect against UVB damage in all concentrations tested[1]. About 50% inhibition of bacterial killing is observed when 12 ng of purified type 3 CPS is added to the OPKA. The addition of 30 μL of mouse serum post-i.p. infection with WU2 (containing 0.4 to 0.7 μg/mL released type 3 CPS) shows 26% to 52% inhibition of bacterial killing, comparable to what is observed when an equivalent amount of purified CPS is added[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

258.23

Formula

C14H10O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
Kinase Assay
[2]

To measure the inhibitory effect of releaseing type 3-CPs on bacteria killing, an OPKA is performed with the addition of culture supernatant or mouse serum obtained at 24 h following i.p. injection with 103 CFU of the S. pneumoniae WU2 strain. In each well, 10 μL of diluted rabbit serum is mixed with 10 μL of strain WU2 (1,000 CFU) and 10 μL of culture supernatant or mouse serum for 30 min at room temperature before HL-60 cells and complement are added. The percent inhibition of bacterial killing is compared to that with the OPKA with the addition of ΔCPS WU2 culture supernatant or naive mouse serum containing no 3-CPs[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

3-CPs 相关分类

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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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3-CPs
目录号:
HY-U00265
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