1. Membrane Transporter/Ion Channel Neuronal Signaling Metabolic Enzyme/Protease
  2. GABA Receptor Drug Metabolite
  3. 4-Hydroxymidazolam

4-Hydroxymidazolam  (Synonyms: 4-羟基咪达唑仑)

目录号: HY-100050
产品使用指南

4-Hydroxymidazolam 是 Midazolam 的一种主要代谢产物。Midazolam 是一种有效的苯二氮卓类药物,具有抗焦虑活性。

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4-Hydroxymidazolam Chemical Structure

4-Hydroxymidazolam Chemical Structure

CAS No. : 59468-85-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Hydroxymidazolam is a major metabolite of Midazolam. Midazolam is a potent benzodiazepine with anxiolytic properties.

体外研究
(In Vitro)

Midazolam is metabolized to 1'- and 4-hydroxymidazolam by CYP3A4 and CYP3A5 and is further metabolized to glucuronide conjugates by UDP-glucuronosyltransferases (UGTs)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

341.77

Formula

C18H13ClFN3O

CAS 号
中文名称

4-羟基咪达唑仑

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
4-Hydroxymidazolam
目录号:
HY-100050
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