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Regorafénib N-oxyde M2 

目录号: HY-I0678
产品使用指南

Regorafénib N-oxyde M2 是 Regorafenib 的活性代谢物。Regorafenib 是一种多靶点抑制剂,对于 VEGFR1/2/3,PDGFRβ,Kit,RET 和 Raf-1 的 IC50 值分别为 13/4.2/46,22,7,1.5 和 2.5 nM。

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Regorafénib N-oxyde M2 Chemical Structure

Regorafénib N-oxyde M2 Chemical Structure

CAS No. : 835621-11-9

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥1210 In-stock
5 mg ¥1100 In-stock
10 mg ¥1800 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.0048 mL 10.0239 mL 20.0477 mL
5 mM 0.4010 mL 2.0048 mL 4.0095 mL
10 mM 0.2005 mL 1.0024 mL 2.0048 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

498.81

Formula

C₂₁H₁₅ClF₄N₄O₄

CAS No.

835621-11-9

SMILES

FC1=CC(OC2=CC=[N+]([O-])C(C(NC)=O)=C2)=CC=C1NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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产品名称:
Regorafénib N-oxyde M2
目录号:
HY-I0678
需求量: