1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR

7-Chlorokynurenic acid sodium salt 

目录号: HY-100811A 纯度: 99.79%
产品使用指南

7-Chlorokynurenic acid sodium salt 是 N-甲基-D-天冬氨酸受体复合物甘氨酸调节位点上的选择性拮抗剂,并且能有效抑制谷氨酸被重吸收到突触小泡中, 其 Ki 值 0.59 μM。

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7-Chlorokynurenic acid sodium salt Chemical Structure

7-Chlorokynurenic acid sodium salt Chemical Structure

CAS No. : 1263094-00-3

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥935 In-stock
10 mg ¥850 In-stock
50 mg ¥3400 In-stock
100 mg ¥6200 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of 7-Chlorokynurenic acid sodium salt:

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Description

7-Chlorokynurenic acid sodium salt is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex and also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM.

IC50 & Target

N-methyl-D-aspartate receptor[1]
Ki: 0.59 μM (reuptake of glutamate)[1]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 4.0718 mL 20.3591 mL 40.7183 mL
5 mM 0.8144 mL 4.0718 mL 8.1437 mL
10 mM 0.4072 mL 2.0359 mL 4.0718 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

245.59

Formula

C₁₀H₅ClNNaO₃

CAS No.

1263094-00-3

SMILES

O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)[O-].[Na+]

Storage

4°C, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 33.67 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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产品名称:
7-Chlorokynurenic acid sodium salt
目录号:
HY-100811A
需求量: