1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. ACTH (1-14)

ACTH (1-14)  (Synonyms: Adrenocorticotropic Hormone Fragment 1-14)

目录号: HY-P1582
产品使用指南

ACTH (1-14) 是促肾上腺皮质激素的多肽片段,后者能够促进皮质醇的释放。

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Custom Peptide Synthesis

ACTH (1-14) Chemical Structure

ACTH (1-14) Chemical Structure

CAS No. : 25696-21-3

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2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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ACTH (1-14) 的其他形式现货产品:

Customer Review

Other Forms of ACTH (1-14):

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ACTH (1-14) is a fragment of adrenocorticotrophin, which regulates cortisol and androgen production.

体外研究
(In Vitro)

Adrenocorticotropic hormone (ACTH) is a tropic hormone produced by the anterior pituitary, regulates cortisol and androgen production and is associated with Addison disease, Cushing syndrome and Cushing disease[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1680.88

Formula

C77H109N21O20S

CAS 号
Sequence

Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly

Sequence Shortening

SYSMEHFRWGKPVG

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
ACTH (1-14)
目录号:
HY-P1582
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