1. Anti-infection
  2. Fungal

AN2718 

目录号: HY-100527
产品使用指南

AN2718 通过 OBORT 机制抑制蛋白质的合成,从而抑制真菌的生长。

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AN2718 Chemical Structure

AN2718 Chemical Structure

CAS No. : 174672-06-1

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10 mg ¥900 Get quote
25 mg ¥1800 Get quote
50 mg ¥2900 Get quote
100 mg ¥4900 Get quote

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Description

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

IC50 & Target

Fungal[1].

In Vitro

AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus, and from yeasts, C. albicans, with an IC50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T.mentagrophytes[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9386 mL 29.6930 mL 59.3859 mL
5 mM 1.1877 mL 5.9386 mL 11.8772 mL
10 mM 0.5939 mL 2.9693 mL 5.9386 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

168.39

Formula

C₇H₆BClO₂

CAS No.

174672-06-1

SMILES

OB1OCC2=CC(Cl)=CC=C21

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
AN2718
目录号:
HY-100527
需求量:

AN2718

Cat. No.: HY-100527