1. Neuronal Signaling
    Stem Cell/Wnt
  2. γ-secretase

BI-1408 

目录号: HY-112282
产品使用指南

BI-1408 是一种有效的 γ 分泌酶调节剂,作用于 42IC50 为 0.04 μM。

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BI-1408 Chemical Structure

BI-1408 Chemical Structure

CAS No. : 2231075-94-6

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Description

BI-1408 is a potent γ secretase modulator with an IC50 of 0.04 μM for 42[1].

IC50 & Target

IC50: 40 nM (Aβ42)[1]

References
Molecular Weight

390.46

Formula

C₂₂H₂₃FN₆

CAS No.

2231075-94-6

SMILES

CC1=CC(F)=CC=C1C2=CC=CN3C2=NC(N[C@@H]4CCC(N(CC)N=C5)=C5C4)=N3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
BI-1408
目录号:
HY-112282
需求量:

BI-1408

Cat. No.: HY-112282