1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Clenbuterol hydrochloride

Clenbuterol hydrochloride  (Synonyms: NAB-365 hydrochloride)

目录号: HY-B1614 纯度: 99.98%
COA 产品使用指南

Clenbuterol (NAB-365) hydrochloride 是一种选择性 β2 肾上腺素能激动剂,可增强骨骼肌强度和肥大。Clenbuterol hydrochloride 诱导生长因子 mRNA,激活星形胶质细胞,保护大鼠脑组织免受缺血损伤。

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Clenbuterol hydrochloride Chemical Structure

Clenbuterol hydrochloride Chemical Structure

CAS No. : 21898-19-1

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Other Forms of Clenbuterol hydrochloride:

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查看 Adrenergic Receptor 亚型特异性产品:

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Clenbuterol (NAB-365) hydrochloride, a selective β2-adrenergic agonist, enhances skeletal muscle strength and hypertrophy. Clenbuterol hydrochloride induces growth factor mRNA, activates astrocytes, and protects rat brain tissue against ischemic damage[1][2][3].

体外研究
(In Vitro)

Clenbuterol increases lipolysis in rat primary adipocytes compared with control. Free glycerol release into the culture medium is 158% and 190% of control values in cultures containing 0.1, or 1 μM Clenbuterol, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Clenbuterol (0.01-0.5 mg/kg; i.p.; male Long-Evans rats) hydrochloride reduces the cortical infarct volume in Long-Evans rats as measured 7 days after permanent occlusion of the middle cerebral artery[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

313.65

Formula

C12H19Cl3N2O

CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸克伦特罗

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 83.33 mg/mL (265.68 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.1883 mL 15.9413 mL 31.8827 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.98%

参考文献
Cell Assay
[1]

MTS assay is performed to determine the number of viable cells in culture. Cells are treated with 0 (vehicle only), 0.1, or 1 μM Clenbuterol for 6, 12, 24, or 48 h. The absorbance is measured at 490 nm in a plate reader determine the formazan concentration, which is proportional to the number of living cells in culture[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Administration
[2]

Rats:
Rats are randomly divided into two treatment groups. The control group is provided with standard chow and water ad libitum for 3 weeks, while the Clenbuterol group is provided with standard chow and treated for 3 weeks with Clenbuterol administered via the drinking water (30 mg Clenbuterol/L). Body weight and the amount of water consumed are recorded twice each week. After 3 wk, the animals are anesthetized and hindlimb muscles are excised[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

Clenbuterol hydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1883 mL 15.9413 mL 31.8827 mL 79.7067 mL
5 mM 0.6377 mL 3.1883 mL 6.3765 mL 15.9413 mL
10 mM 0.3188 mL 1.5941 mL 3.1883 mL 7.9707 mL
15 mM 0.2126 mL 1.0628 mL 2.1255 mL 5.3138 mL
20 mM 0.1594 mL 0.7971 mL 1.5941 mL 3.9853 mL
25 mM 0.1275 mL 0.6377 mL 1.2753 mL 3.1883 mL
30 mM 0.1063 mL 0.5314 mL 1.0628 mL 2.6569 mL
40 mM 0.0797 mL 0.3985 mL 0.7971 mL 1.9927 mL
50 mM 0.0638 mL 0.3188 mL 0.6377 mL 1.5941 mL
60 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.3284 mL
80 mM 0.0399 mL 0.1993 mL 0.3985 mL 0.9963 mL
100 mM 0.0319 mL 0.1594 mL 0.3188 mL 0.7971 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Clenbuterol hydrochloride
目录号:
HY-B1614
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