2. 天然产物
  3. 疾病研究领域 植物 黄酮类 酚类
  4. 蝶形花科 癌症 黄酮醇 多酚类
  5. 扁茎黄芪
  6. Complanatoside A

Complanatoside A  (Synonyms: 沙苑子苷 A)

目录号: HY-N0624
产品使用指南

摩尔计算器

Complanatoside A是从黄芪分离的黄酮醇糖苷，目前它被用作2010版中国药典 A. complanatus 的质量控制指数。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Complanatoside A Chemical Structure

Complanatoside A Chemical Structure

CAS No. : 146501-37-3

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规格 价格 是否有货 数量
5 mg
询价
10 mg
询价
25 mg
询价
1 mg ￥3222
询价
5 mg   询价  
10 mg   询价  

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Customer Review

Complanatoside A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Complanatoside A is a flavonol glycoside isolated from Astragalus complanatus, and currently it is used as a quality control index for A. complanatus in the 2010 edition of the Chinese Pharmacopoeia.

体外研究
(In Vitro)

A simple and sensitive LC-MS/MS method is developed for the determination of complanatoside A in rat plasma over the range of 2.3–575 ng/mL. Complanatoside A is extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The lower limit of quantification is established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) are less than 7.9%, and accuracies are between 94.0 and 105.1%. Matrix effect is acceptable (97.9–103.0%) and extraction recovery is reproducible (88.5–94.4%). Complanatoside A is stable in the investigated conditions. The method is applied to the pharmacokinetics of complanatoside A in rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Complanatoside A 相关抗体:
分子量

642.52

Formula

C27H30O18
CAS 号
中文名称

沙苑子苷 A
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro: 

DMSO 中的溶解度 : ≥ 35.7 mg/mL (55.56 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.5564 mL 7.7819 mL 15.5637 mL
5 mM 0.3113 mL 1.5564 mL 3.1127 mL
查看完整储备液配制表

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献
Animal Administration
[1]

Rats: The rats are fasted for 12 h before the experiment. Complanatoside A is formulated in water and a single dose of 30 mg/kg is administered by oral gavage. Blood samples are obtained from the vena orbitalis just prior to dose and at 0.083, 0.167, 0.25, 0.5, 0.75, 1, 2, 3, 5, 7, 10 and 14 h after administration. After centrifugation at 6000g for 10 min, the upper plasma is collected and stored at–20°C before analysis. The data are calculated by Drug&Statistics software[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

完整储备液配制表

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5564 mL 7.7819 mL 15.5637 mL 38.9093 mL
5 mM 0.3113 mL 1.5564 mL 3.1127 mL 7.7819 mL
10 mM 0.1556 mL 0.7782 mL 1.5564 mL 3.8909 mL
15 mM 0.1038 mL 0.5188 mL 1.0376 mL 2.5940 mL
20 mM 0.0778 mL 0.3891 mL 0.7782 mL 1.9455 mL
25 mM 0.0623 mL 0.3113 mL 0.6225 mL 1.5564 mL
30 mM 0.0519 mL 0.2594 mL 0.5188 mL 1.2970 mL
40 mM 0.0389 mL 0.1945 mL 0.3891 mL 0.9727 mL
50 mM 0.0311 mL 0.1556 mL 0.3113 mL 0.7782 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Complanatoside A146501-37-3沙苑子苷 AOthersInhibitorinhibitorinhibit

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