1. Terpenoids and Glycosides

Glycyrrhizic acid (Synonyms: Glycyrrhizin)

目录号: HY-N0184 纯度: >98.0%
Data Sheet SDS 产品使用指南

Glycyrrhizic acid 是甘草里面的活性成分三萜皂苷,具有抗肿瘤、抗糖尿病等功效。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务
Glycyrrhizic acid Chemical Structure

Glycyrrhizic acid Chemical Structure

CAS No. : 1405-86-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Price Stock Quantity
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥913 In-stock
25 g ¥830 In-stock
100 g ¥2480 Get quote
> 100 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products

Glycyrrhizic acid 相关产品

Related Screening Libraries:

  • 生物活性

  • 实验参考方法

  • 技术信息

  • 纯度 & 产品资料

  • 参考文献

Description

Glycyrrhizic acid is a triterpenoid saponinl, extracted from the licorice root, with anti-tumor, anti-diabetic activities.

In Vitro

Glycyrrhizic acid shows a series of anti-cancer-related pharmacological activities, such as broad-spectrum anti-cancer ability, resistance to the tissue toxicity caused by chemotherapy and radiation, drug absorption enhancing effects and anti-multidrug resistance (MDR) mechanisms, as a carrier material in drug delivery systems[1]. In intestinal NCI-H716 cells that secretes GLP-1, Glycyrrhizic acid promotes GLP-1 secretion with a marked elevation of calcium levels. Glycyrrhizic acid can enhance GLP-1 secretion through TGR5 activation[2].

In Vivo

In type 1-like diabetic rats induced by streptozotocin (STZ-treated rats), Glycyrrhizic acid increases the level of plasma GLP-1, which is blocked by triamterene at a dose sufficient to inhibit Takeda G-protein-coupled receptor 5 (TGR5)[1].

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.2152 mL 6.0759 mL 12.1517 mL
5 mM 0.2430 mL 1.2152 mL 2.4303 mL
10 mM 0.1215 mL 0.6076 mL 1.2152 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

822.93

Formula

C₄₂H₆₂O₁₆

CAS No.

1405-86-3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 10 mM

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

   电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Glycyrrhizic acid
目录号:
HY-N0184
需求量: