1. Metabolic Enzyme/Protease Autophagy
  2. HMG-CoA Reductase (HMGCR) Autophagy
  3. HMG499

HMG499是有效,选择性的 HMG-CoA还原酶 抑制剂, EC50为 0.41 μM。HMG499可预防他汀类活性分子诱导的HMGCR积聚,降低血清胆固醇水平,减少动脉粥样硬化。

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HMG499 Chemical Structure

HMG499 Chemical Structure

CAS No. : 2416941-68-7

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规格 价格 是否有货 数量
5 mg ¥8120
10 - 12 周
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis[1].

IC50 & Target

IC50: 0.41 μM (HMG-CoA reductase)[1]

分子量

498.78

Formula

C33H54O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
HMG499
目录号:
HY-114316
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