1. Metabolic Enzyme/Protease
  2. Fatty Acid Synthase (FASN)
  3. HS80

HS-80 是 Fasnall 的一种对映体,Fasnall 是一种选择性脂肪酸合酶 (FASN) 抑制剂。HS-80 能够抑制氚化乙酸盐掺入脂质中,IC50 为 7.13 μM。

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HS80 Chemical Structure

HS80 Chemical Structure

CAS No. : 2138838-57-8

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.

IC50 & Target

FASN[1]

体外研究
(In Vitro)

Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

338.47

Formula

C19H22N4S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HS80
目录号:
HY-112522A
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