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  4. Ipenoxazone

Ipenoxazone  (Synonyms: 伊培沙宗; MLV-6976; NC-1200)

目录号: HY-100159
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摩尔计算器

Ipenoxazone 是一种强效的中枢性肌肉松弛剂。

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Ipenoxazone Chemical Structure

Ipenoxazone Chemical Structure

CAS No. : 104454-71-9

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Ipenoxazone 相关抗体

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  • 生物活性

  • 实验参考方法

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  • 参考文献

生物活性

Ipenoxazone is a potent and centrally acting muscle relaxant.

体内研究
(In Vivo)

Ipenoxazone is a potent and centrally acting muscle relaxant[1]. An intravenous injection of 2 mg/kg Ipenoxazone causes a reduction of electromyographic activity which reaches a maximum within 3 min after the injection. Within 1 min after the injection of Ipenoxazone at a dose of 4 mg/kg, the blood pressure changes from a control level of 138±9 mmHg to a minimum level of 98±9 mmHg (n=6) but it rapidly returns to the control level within 1 to 2 min, while the rigidity is still reduced significantly at that time. High doses (greater than 30 mg/kg i.p.) of Ipenoxazone produces a transient and dose-dependent sedation in almost all mice about 5 min after its administration[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

358.52

Formula

C22H34N2O2
CAS 号
中文名称

伊培沙宗
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Animal Administration
[1]

Experiments are performed on 31 adult male rats (Wistar 310 to 430 g, 3 to 7 months of age) anesthetized with chloralose-urethane (50 and 500 mg/kg i.p., respectively). Ipenoxazone is administrated i.v. at 0.05 to 0.1 mL/100 g body weight (20 to 40 s per injection). These four different doses of Ipenoxazone (0.3, 1, 3 and 10 mg/kg) are administrated cumulatively, from small doses to larger doses. It is usually waited about 10 to 30 min between each trial or until all effects of the drug on the bladder have disappeared[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Ipenoxazone 相关分类

  • 摩尔计算器

  • 稀释计算器

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ipenoxazone104454-71-9MLV-6976 NC-1200伊培沙宗MLV6976MLV 6976NC1200NC 1200NC-1200OthersInhibitorinhibitorinhibit

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