1. Immunology/Inflammation
  2. NO Synthase

L-NIO dihydrochloride 

目录号: HY-100986 纯度: >95.0%
产品使用指南

L-NIO dihydrochloride 是一种有效、非选择性、NADPH 依赖性的一氧化氮合酶 (NOS) 抑制剂,对神经元型 (nNOS)、内皮型 (eNOS)、和诱生型 (iNOS) 一氧化氮合酶的 Ki 值分别为 1.7,3.9,3.9 μM。L-NIO dihydrochloride 可诱导大鼠持续局灶性缺血性脑梗死。

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L-NIO dihydrochloride Chemical Structure

L-NIO dihydrochloride Chemical Structure

CAS No. : 159190-44-0

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Size Price Stock Quantity
10 mM * 1 mL in Water ¥1089 In-stock
5 mg ¥990 In-stock
10 mg ¥1750 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Description

L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with Kis of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively[1][2]. L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats[2].

IC50 & Target

Ki: 1.7 μM (nNOS), 3.9 μM (eNOS), 3.9 μM (iNOS)[1]

References
Molecular Weight

246.13

Formula

C₇H₁₇Cl₂N₃O₂

CAS No.

159190-44-0

SMILES

N[C@@H](CCCNC(C)=N)C(O)=O.[H]Cl.[H]Cl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >95.0%

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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产品名称:
L-NIO dihydrochloride
目录号:
HY-100986
需求量:

L-NIO dihydrochloride

Cat. No.: HY-100986