1. Anti-infection
  2. Reverse Transcriptase
    HIV

Loviride (Synonyms: R 89439)

目录号: HY-15355
产品使用指南

Loviride (R 89439) 是一种非核苷类逆转录酶抑制剂 (NNRTI),对 HIV-1 逆转录酶的 IC50 值为 0.3 µM。Loviride (R 89439) 可抑制 MT-4 细胞中的 HIV-1,HIV-2 和 SIV 复制。

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Loviride Chemical Structure

Loviride Chemical Structure

CAS No. : 147362-57-0

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Description

Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 µM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells[1].

IC50 & Target

IC50: 0.3 µM (Reverse transcriptase)[1]

In Vitro

Loviride (0.01 µM) inhibits HIV-1(IIIB) replication in MT-4 cells, also inhibits HIV-2 and SIV, with EC50s of 85.5, 7.4 µM for HIV-2 (ROD), HIV-2 (EHO), and 11.4, 28.5, 57.0 µM for SIV (mac251), SIV (agm3), SIV (mndGB1), respectively[1].

References
Molecular Weight

351.23

Formula

C₁₇H₁₆Cl₂N₂O₂

CAS No.

147362-57-0

SMILES

O=C(N)C(NC1=C(C(C)=O)C=CC(C)=C1)C2=C(Cl)C=CC=C2Cl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Loviride
目录号:
HY-15355
需求量:

Loviride

Cat. No.: HY-15355