2. GPCR/G Protein
  3. GnRH Receptor
  4. Luteinizing Hormone Releasing Hormone (LH-RH), salmon

Luteinizing Hormone Releasing Hormone (LH-RH), salmon  (Synonyms: Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH)

目录号: HY-P0243 纯度: 98.82%
COA 产品使用指南

摩尔计算器

Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) 是在下丘脑中合成的垂体前体十肽，在控制生殖功能中起关键作用。

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Custom Peptide Synthesis

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Chemical Structure

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Chemical Structure

CAS No. : 86073-88-3

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规格 价格 是否有货 数量
1 mg ￥880
In-stock
5 mg ￥1950
In-stock
10 mg ￥3500
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Luteinizing Hormone Releasing Hormone (LH-RH), salmon 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

体外研究
(In Vitro)

Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Luteinizing Hormone Releasing Hormone (LH-RH), salmon 相关抗体:
分子量

1212.31

Formula

C60H73N15O13
CAS 号
性状

固体

颜色

White to off-white

Sequence

{Glp}-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2
Sequence Shortening

{Glp}-HWSYGWLPG-NH2
中文名称

黄体激素释放激素 (LH-RH),蛙鱼
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Luteinizing Hormone Releasing Hormone (LH-RH), salmon 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Luteinizing Hormone Releasing Hormone (LH-RH), salmon86073-88-3Salmon GnRH Salmon gonadotropin-releasing hormone sGnRH黄体激素释放激素 (LH-RH),蛙鱼GnRH ReceptorGonadotropin releasing hormone receptorGNRHRInhibitorinhibitorinhibit

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目录号：
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