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Miridesap (Synonyms: CPHPC; Ro63-8695; GSK2315698)

目录号: HY-101861
产品使用指南

Miridesap 是血清淀粉样蛋白 P 组分 (SAP) 的配体,能抑制和解离 SAP 与淀粉状蛋白原纤维的结合。

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Miridesap Chemical Structure

Miridesap Chemical Structure

CAS No. : 224624-80-0

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Size Price Stock Quantity
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥550 In-stock
5 mg ¥500 In-stock
10 mg   Get quote  
50 mg   Get quote  

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Description

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.

IC50 & Target

SAP[1]

In Vitro

Miridesap is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles[1]. Miridesap depletes circulating SAP almost completely but leaves some SAP in amyloid deposits for specific recognition by subsequently administered therapeutic anti-SAP antibodies[2].

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.9380 mL 14.6899 mL 29.3798 mL
5 mM 0.5876 mL 2.9380 mL 5.8760 mL
10 mM 0.2938 mL 1.4690 mL 2.9380 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

340.37

Formula

C₁₆H₂₄N₂O₆

CAS No.

224624-80-0

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 300 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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产品名称:
Miridesap
目录号:
HY-101861
需求量: