1. Metabolic Enzyme/Protease
  2. Isocitrate Dehydrogenase (IDH)

Mutant IDH1-IN-4 

目录号: HY-114459 纯度: >99.0%
产品使用指南

Mutant IDH1-IN-4 (compound 434) 是一种突变型异柠檬酸脱氢酶 1 (IDH 1) 的抑制剂,其对R132H、HT1080 和U87R132H细胞中的突变型IDH 1 的IC50 值 ≤ 0.5 μM。

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Mutant IDH1-IN-4 Chemical Structure

Mutant IDH1-IN-4 Chemical Structure

CAS No. : 1416270-18-2

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥9350 In-stock
5 mg ¥8500 In-stock
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Description

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1].

IC50 & Target

IC50: ≤ 0.5 μM (mutant IDH 1 in cells)[1].

References
Molecular Weight

438.56

Formula

C₂₅H₃₄N₄O₃

CAS No.

1416270-18-2

SMILES

N#CC1=C(N2C[C@@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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产品名称:
Mutant IDH1-IN-4
目录号:
HY-114459
需求量:

Mutant IDH1-IN-4

Cat. No.: HY-114459