1. GPCR/G Protein Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. Neuropeptide Y (13-36), amide, human

Neuropeptide Y (13-36), amide, human  (Synonyms: Neuropeptide Y (13-36), human)

目录号: HY-P1480 纯度: 98.14%
COA 产品使用指南

Neuropeptide Y (13-36), amide, human 是选择性的神经肽 Y2 受体 (neuropeptide Y2 receptor) 的激动剂。

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Custom Peptide Synthesis

Neuropeptide Y (13-36), amide, human Chemical Structure

Neuropeptide Y (13-36), amide, human Chemical Structure

CAS No. : 122341-40-6

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Neuropeptide Y (13-36), amide, human is a selective neuropeptide Y2 receptor agonist[1].

IC50 & Target[2]

NPY Y2 receptor

 

体内研究
(In Vivo)

Neuropeptide Y (13-36) (intraventricular injection; 25-3000 pmol) produces a dose-dependent increase (up to 14%; ED50 value of 0.3 nmol for overall effects and 0.97 nmol for the peak effects) in mean arterial blood pressure in the awake, unrestrained male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].
Neuropeptide Y (13-36) (intracerebroventricular injection; 50 ng; alone; injected 30 and 15 min before measurements) injected into naïve mice impairs social novelty preference, but not sociability, and this effect is inhibited by the NPY Y2 receptor antagonist BIIE 0246[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male ICR mice (age 4-7 weeks)[2]
Dosage: 50 ng/mouse
Administration: Intracerebroventricular injection
Result: Significantly decreased interaction time with the new stranger mouse in session 3 that NPY 13-36.
分子量

3000.40

Formula

C134H207N41O36S

CAS 号
性状

固体

颜色

White to off-white

Sequence

Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2

Sequence Shortening

PAEDMARYYSALRHYINLITRQRY-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

纯度 & 产品资料
参考文献

Neuropeptide Y (13-36), amide, human 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Neuropeptide Y (13-36), amide, human
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