1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. PF-06700841

PF-06700841 

目录号: HY-112708
产品使用指南

PF-06700841是 JAK1TYK2 的双抑制剂,IC50 分别为17 和 23 nM。抗炎活性。

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PF-06700841 Chemical Structure

PF-06700841 Chemical Structure

CAS No. : 1883299-62-4

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PF-06700841 的其他形式现货产品:

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Description

PF-06700841 is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].

IC50 & Target

IC50: 17 nM (JAK1), 23 nM (TYK2)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

389.40

Formula

C₁₈H₂₁F₂N₇O

CAS No.

1883299-62-4

SMILES

O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
PF-06700841
目录号:
HY-112708
需求量:

PF-06700841

Cat. No.: HY-112708