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PZ-2891 

目录号: HY-124634
产品使用指南

PZ-2891是一种可口服,能渗透血脑屏障的泛酸激酶 (PANK)变构调节剂,乙酰辅酶A存在下, 可起到正构抑制剂的作用 (IC50=1.3 nM, hPANK3) 和PANK3变构活化作用。

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PZ-2891 Chemical Structure

PZ-2891 Chemical Structure

CAS No. : 2170608-82-7

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥1320 In-stock
5 mg ¥1200 In-stock
10 mg ¥1900 In-stock
50 mg ¥5800 In-stock
100 mg ¥9500 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

PZ-2891 is an oral, allosteric, and brain penetrant pantothenate kinase (PANK) modulator, acting as both an orthosteric inhibitor (IC50=1.3 nM) and an allosteric activator of PANK3 activity in the presence of acetyl-CoA.

IC50 & Target

IC50: 1.3 nM (PANK)[1]

References
Molecular Weight

349.43

Formula

C₂₀H₂₃N₅O

CAS No.

2170608-82-7

SMILES

N#CC1=NN=C(N2CCN(C(CC3=CC=C(C(C)C)C=C3)=O)CC2)C=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
PZ-2891
目录号:
HY-124634
需求量:

PZ-2891

Cat. No.: HY-124634