1. Metabolic Enzyme/Protease
  2. ROR
  3. RORγt Inverse agonist 2

RORγt Inverse agonist 2 

目录号: HY-111748
产品使用指南

RORγt Inverse agonist 2 是具有口服活性的选择性 RORγt 反向激动剂,EC50 为 119 nM。

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RORγt Inverse agonist 2 Chemical Structure

RORγt Inverse agonist 2 Chemical Structure

CAS No. : 1801197-92-1

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Description

RORγt Inverse agonist 2 is a selective, orally active RORγt inverse agonist with an EC50 of 119 nM[1].

IC50 & Target

EC50: 119 nM (RORγt)[1]

In Vitro

RORγt Inverse agonist 2 (Compound 26) is inactive against RORα and RORβ in either inverse agonist or agonist mode (>40 μM)[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

627.54

Formula

C₂₇H₂₅F₈NO₅S

CAS No.

1801197-92-1

SMILES

FC(C(F)(F)F)(C(F)(F)F)C1=CC=C([C@]2(CN(C([C@@H]3CC[C@@H](C(O)=O)CC3)=O)CC2)S(C4=CC=C(F)C=C4)(=O)=O)C=C1

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Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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产品名称:
RORγt Inverse agonist 2
目录号:
HY-111748
需求量:

RORγt Inverse agonist 2

Cat. No.: HY-111748