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RXFP3/4 agonist 1 

目录号: HY-111583
产品使用指南

RXFP3/4 agonist 1 是一种松弛素家族肽 3/4 受体 (RXFP3/4) 抑制剂,EC50 值分别为 82 和 2 nM。能够增强大鼠的食物摄取量。

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RXFP3/4 agonist 1 Chemical Structure

RXFP3/4 agonist 1 Chemical Structure

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Description

RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats[1].

IC50 & Target

EC50: 82 nM (RXFP3), 2 nM (RXFP4)[1]

In Vitro

RXFP3/4 agonist 1 (Compound 4) inhibits orskolin-stimulated cAMP accumulation in CHO-K1 cells stably overexpressing RXFP3 and RXFP4, with EC50s of 12.8 and 1.6 nM, respectively[1].

References
Molecular Weight

383.87

Formula

C₂₀H₂₂ClN₅O

SMILES

CCC1=C(NC=C2/C=N/NC(NCCC3=CC=C(Cl)C=C3)=N)C2=CC(O)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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产品名称:
RXFP3/4 agonist 1
目录号:
HY-111583
需求量:

RXFP3/4 agonist 1

Cat. No.: HY-111583