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SZ1676 是 SZ1677 的衍生物,SZ1677 是一种神经肌肉阻滞剂。

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SZ1676 Chemical Structure

SZ1676 Chemical Structure

CAS No. : 159325-23-2

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Top Publications Citing Use of Products
  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

SZ1676 is a derivative of SZ1677, which is a neuromuscular blocking agent.

体内研究
(In Vivo)

SZ1676 is the 3-acetoxy derivative[1]. The neuromuscular (NM) effects of SZ1676 and SZ1677 are compared in beagle dogs. SZ1677 (ED90=19.2±2.6 μg/kg) is 1.86 times more potent than SZ1676 (ED90=35.8±2.5 μg/kg)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

707.78

Formula

C37H59BrN2O6

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
Animal Administration
[2]

Dogs[2]
Beagle dogs of about 10 kg body weight, anesthetized with isofurane are intubated and mechanically ventilated with O2, One fore-leg is fixed above the elbow and the wrist and the ulnar nerve is stimulated at the elbow, percutaneously,with supramaximal electrical impulses of 0.2 ms duration at 0.1 or 0.4 Hz.The force of flxion of the paw (P) is quantitated and contiuously recorded, At first the ED50, ED90 and ED95 of the 2 muscle relaxants (MR) are determined.Thirty min after maximal spontaneous recovery of P,the calculated 2×ED90 is injected and the time course ol the NM and circulatory effects are determined.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

SZ1676 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SZ1676
目录号:
HY-U00162
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