1. GPCR/G Protein
  2. Glucagon Receptor

Glucagon Receptor

Glucagon receptor is in the G protein-coupled receptor family, that is important in controlling blood glucose levels. The glucagon receptor is a 62 kDa protein that is activated by glucagon and is a member of the class B G-protein coupled family of receptors, coupled to G alpha i, Gs and to a lesser extent G alpha q. Stimulation of the receptor results in activation of adenylate cyclase and increased levels of intracellular cAMP. In humans, the glucagon receptor is encoded by the GCGR gene. Glucagon receptors are mainly expressed in liver and in kidney with lesser amounts found in heart, adipose tissue, spleen, thymus, adrenal glands, pancreas, cerebral cortex, and gastrointestinal tract.

Glucagon Receptor 相关产品 (27):

Cat. No. Product Name Effect Purity
  • HY-13443
    Exendin-4 Activator 98.96%
    Exendin-4是由39个氨基酸组成的多肽。它是长效的glucagon-like peptide-1受体激动剂,IC50值为3.22 nM。
  • HY-P0082
    Glucagon
    Glucagon是一个肽激素,对代谢性疾病有很好的功能。
  • HY-P0014
    Liraglutide Agonist 99.96%
    Liraglutide 是一种胰高血糖素样肽-1 (GLP-1) 受体激动剂,用于治疗 2 型糖尿病。
  • HY-50663
    MK 0893 Antagonist 99.22%
    MK 0893 是一种有效的,选择性的 glucagon receptor 拮抗剂,IC50 值为 6.6 nM,选择性是对 GIPR,PAC1,GLP-1R,VPAC1 和 VPAC2 的 200 多倍。
  • HY-19904
    Adomeglivant Antagonist 99.55%
    Adomeglivant是一个强的,有选择性的胰高血糖素受体拮抗剂。
  • HY-P0120
    Dulaglutide Agonist
    Dulaglutide 是胰高血糖素样肽-1 (GLP-1) 受体激动剂。
  • HY-P1458
    Glucagon-Like Peptide (GLP) I (7-36), amide, human
    Glucagon-Like Peptide (GLP) I (7-36), amide, human是刺激胰岛素分泌的生理性肠降血糖素。
  • HY-P0054
    GLP-1(7-36) Acetate 98.42%
    GLP-1(7-36)是一个主要的肠道激素,能够从β细胞中刺激胰岛素的分泌。
  • HY-P0264
    Exendin 9-39 Antagonist
    Exendin (9-39) 是特异竞争性的 glucagon-like peptide-1 受体激动剂。
  • HY-13443A
    Exendin-4 Acetate Activator 98.69%
    Exendin-4 acetate是由39个氨基酸组成的多肽。它是长效的glucagon-like peptide-1受体激动剂,IC50值为3.22 nM。
  • HY-P0119
    Lixisenatide Inhibitor 98.36%
    Lixisenatide抑制glucagon的释放,能有效的减少postprandial glucago, 在糖尿病治疗中有促进作用。
  • HY-P0055
    GLP-1(7-37) Inhibitor 98.62%
    GLP-1(7-37)是前体肽GLP-1(1-37)产生的一种促胰岛素多肽。
  • HY-12525
    LGD-6972 Antagonist >98.0%
    LGD-6972是一种胰高血糖素受体拮抗剂。
  • HY-19947
    Glucagon receptor antagonists-4 Antagonist
    Glucagon receptor antagonists-4是一个高度有效的胰高血糖素受体拮抗剂。
  • HY-10036
    Glucagon receptor antagonists-1 Antagonist
    Glucagon receptor antagonists-1是高活性高血糖素受体拮抗剂。
  • HY-50158
    Glucagon receptor antagonists-2 Antagonist
    Glucagon receptor antagonists-2是高活性高血糖素受体拮抗剂。
  • HY-P0165
    Taspoglutide Agonist
    Taspoglutide是为治疗2型糖尿病而开发的长效GLP-1受体激动剂, EC50值为0.06 nM。
  • HY-50159
    Glucagon receptor antagonists-3 Antagonist
    Glucagon receptor antagonists-3是高活性高血糖素受体拮抗剂。
  • HY-P1231
    GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS 99.03%
    GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS是Exendin-4多肽衍生物。
  • HY-P1226
    HAEGTFTSD Agonist 98.04%
    HAEGTFTSD是GLP-1多肽N-端的1-9残基。
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