1. Vitamin D Related/Nuclear Receptor
  2. Androgen Receptor
  3. Topterone

Topterone  (Synonyms: Win 17665)

目录号: HY-U00198
产品使用指南

Topterone 是一种局部抗雄激素。

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Topterone Chemical Structure

Topterone Chemical Structure

CAS No. : 60607-35-4

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Topterone is a topical antiandrogen.

IC50 & Target

Androgen[1]

体内研究
(In Vivo)

Topterone, is administered parenterally or topically to rats, rabbits or hamsters to determine its endocrine profile. Systemic administration demonstrates that Topterone is both antiandrogenic and progestational. Topical application fails to elicit a systemic antiandrogenic response at 1 g/kg/day and only a minimal progestational response is seen at 32 mg/kg/day. No other endocrine activities are detected[1]. Topterone inhibits stimulation of flank organ development of castrated immature male hamsters by both testosterone and dihydrotestosterone, whereas Progesterone inhibits the stimulation by only testosterone. Topical application of Topterone, has been shown to cause a regression in the development of the flank organ[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

330.50

Formula

C22H34O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Topterone
目录号:
HY-U00198
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