1. Protein Tyrosine Kinase/RTK
  2. ALK
    ROS
  3. WY-135

WY-135 

目录号: HY-111416
产品使用指南

WY-135是ALK (IC50=1.4 nM) 和 ROS1 (IC50=1.1 nM) 的双抑制剂。

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WY-135 Chemical Structure

WY-135 Chemical Structure

CAS No. : 2163060-83-9

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Description

WY-135 is a ALK (IC50=1.4 nM) and ROS1 (IC50=1.1 nM) dual inhibitor.

IC50 & Target

IC50: 1.4 nM (ALK), 1.1 nM (ROS1)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

612.15

Formula

C₂₈H₃₄ClN₉O₃S

CAS No.

2163060-83-9

SMILES

CC(C)S(C1=C(NC2=NC(NC3=C(OC)C=C(N4C=C(CN5CCN(C)CC5)N=N4)C=C3)=NC=C2Cl)C=CC=C1)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
WY-135
目录号:
HY-111416
需求量:

WY-135

Cat. No.: HY-111416