1. Cell Cycle/DNA Damage
    PI3K/Akt/mTOR
  2. DNA-PK

(R)-Nedisertib (Synonyms: (R)-M3814)

目录号: HY-101570A
产品使用指南

(R)-Nedisertib ((R)-M3814) 是一种活性较弱的 Nedisertib 的 R 型异构体,对 DNA-PKIC50 值为 7-30 nM。

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(R)-Nedisertib Chemical Structure

(R)-Nedisertib Chemical Structure

CAS No. : 1637542-32-5

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥2750 In-stock
5 mg ¥2500 In-stock
10 mg ¥3500 In-stock
25 mg ¥6500 In-stock
50 mg ¥9500 In-stock
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Description

(R)-Nedisertib ((R)-M3814) is a less active R-enantiomer of Nedisertib, with an IC50 in the range of 7-30 nM for DNA-PK[1].

IC50 & Target[1]

DNA-PK

7-30 nM (IC50)

In Vitro

Rac-Nedisertib (Compound 135) less actively inhibits DNA-PK, with an IC50 in the range of 7-30 nM[1].

References
Molecular Weight

481.91

Formula

C₂₄H₂₁ClFN₅O₃

CAS No.

1637542-32-5

SMILES

ClC1=C([C@@H](O)C2=NN=C(OC)C=C2)C=C(C3=C4C=CC(N5CCOCC5)=CC4=NC=N3)C(F)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
(R)-Nedisertib
目录号:
HY-101570A
需求量:

(R)-Nedisertib

Cat. No.: HY-101570A