2. Protein Tyrosine Kinase/RTK
  3. TAM Receptor
  4. Ligritinib

AB801 是一种口服有效的 AXL 受体酪氨酸激酶抑制剂。AB801 通过抑制 AXL 的激酶活性，阻断其下游信号通路。AB801 能够用于癌症、尤其是与化疗联合非小细胞肺癌 (NSCLC) 的研究。

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Ligritinib Chemical Structure

Ligritinib Chemical Structure

CAS No. : 3024588-48-2

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Ligritinib 相关抗体

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Axl Mer Tyro3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AB801 is an orally active AXL receptor tyrosine kinase inhibitor. AB801 blocks the downstream signaling pathway by inhibiting the kinase activity of AXL. AB801 can be used in cancer research, especially in combination with chemotherapy for non-small cell lung cancer (NSCLC)[1].

分子量

528.65

Formula

C33H32N6O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ligritinib 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ligritinib3024588-48-2AB801AB 801AB-801TAM ReceptorTyro3AxlMerAXLHEK-293 cellsCD-1 miceSD ratsNu miceInhibitorinhibitorinhibit

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