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  2. Abl Cytosolic Substrate

Abl Cytosolic Substrate 

目录号: HY-P1785
产品使用指南

Abl Cytosolic Substrate是Abl 酪氨酸激酶的底物。Abl 蛋白酪氨酸激酶是v-AbI蛋白酪氨酸激酶的一种截断形式,是Abelson小鼠白血病病毒Gag-Abl融合蛋白的一个伙伴。

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Custom Peptide Synthesis

Abl Cytosolic Substrate Chemical Structure

Abl Cytosolic Substrate Chemical Structure

CAS No. : 168202-46-8

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Description

Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
Molecular Weight

1336.58

Formula

C₆₄H₁₀₁N₁₅O₁₆

CAS No.

168202-46-8

Sequence

{Glu}{Ala}{Ile}{Tyr}{Ala}{Ala}{Pro}{Phe}{Ala}{Lys}{Lys}{Lys}

Sequence Shortening

EAIYAAPFAKKK

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Abl Cytosolic Substrate
目录号:
HY-P1785
需求量:

Abl Cytosolic Substrate

Cat. No.: HY-P1785