1. Protein Tyrosine Kinase/RTK
  2. ALK
  3. ALK-IN-5

ALK-IN-5 

目录号: HY-128569
产品使用指南

ALK-IN-5 是一种高效选择性的,可渗透大脑屏障的 (ALK) 激酶抑制剂,IC50 值为 2.9 nM。

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ALK-IN-5 Chemical Structure

ALK-IN-5 Chemical Structure

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2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Description

ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK), with an IC50 of 2.9 nM[1].

IC50 & Target

IC50: 2.9 nM (ALK)[1]

In Vitro

ALK-IN-5 potently inhibits ALK with cellular IC50 of 27 nM[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

464.49

Formula

C₂₄H₂₅FN₆O₃

SMILES

O=C(C1=CN(C2=NNC(C)=C2)C3=NC(O[C@H](C4=NC=C(F)C=C4)C)=CC=C31)N5C[C@H](C)OCC5

Shipping

Room temperature in continental US; may vary elsewhere

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
ALK-IN-5
目录号:
HY-128569
需求量:

ALK-IN-5

Cat. No.: HY-128569