1. Anti-infection
  2. Bacterial Antibiotic
  3. Bacitracin Zinc

Bacitracin Zinc  (Synonyms: 杆菌肽锌; Zinc bacitracin)

目录号: HY-B0278 纯度: 98.76%
COA 产品使用指南

Bacitracin Zinc (Zinc bacitracin) 是C55-异戊二烯基焦磷酸酯的去磷酸化产物,抑制Tyr从Met-enkephalin分裂,IC50为10 μM。

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Bacitracin Zinc Chemical Structure

Bacitracin Zinc Chemical Structure

CAS No. : 1405-89-6

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bacitracin Zinc (Zinc bacitracin) is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM. Target: Antibacterial Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis [1, 2].

分子量

1486.06

Formula

C66H101N17O16SZn

CAS 号
性状

固体

颜色

White to off-white

中文名称

杆菌肽锌

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

1M HCl 中的溶解度 : 50 mg/mL (33.65 mM; 超声助溶)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6729 mL 3.3646 mL 6.7292 mL
5 mM 0.1346 mL 0.6729 mL 1.3458 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Bacitracin Zinc 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
1M HCl 1 mM 0.6729 mL 3.3646 mL 6.7292 mL 16.8230 mL
5 mM 0.1346 mL 0.6729 mL 1.3458 mL 3.3646 mL
10 mM 0.0673 mL 0.3365 mL 0.6729 mL 1.6823 mL
15 mM 0.0449 mL 0.2243 mL 0.4486 mL 1.1215 mL
20 mM 0.0336 mL 0.1682 mL 0.3365 mL 0.8412 mL
25 mM 0.0269 mL 0.1346 mL 0.2692 mL 0.6729 mL
30 mM 0.0224 mL 0.1122 mL 0.2243 mL 0.5608 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
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