1. Cell Cycle/DNA Damage
  2. CDK
  3. BI-1347

BI-1347 

目录号: HY-120350
产品使用指南

BI-1347 是一种有效的 CDK8 抑制剂,IC50 值为 1.1 nM,详细信息请参考 WO2017202719A1 中的产物 I-003。

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BI-1347 Chemical Structure

BI-1347 Chemical Structure

CAS No. : 2163056-91-3

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Size Price Stock Quantity
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ¥1100 In-stock
5 mg ¥1000 In-stock
10 mg ¥1600 In-stock
50 mg ¥5600 In-stock
100 mg ¥9500 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

BI-1347 is a potent CDK8 inhibitor extracted from patent WO2017202719A1, product I-003, has an IC50 of 1.1 nM[1].

IC50 & Target

IC50: 1.1 nM (CDK8)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (350.71 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8057 mL 14.0284 mL 28.0568 mL
5 mM 0.5611 mL 2.8057 mL 5.6114 mL
10 mM 0.2806 mL 1.4028 mL 2.8057 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
References
Molecular Weight

356.42

Formula

C₂₂H₂₀N₄O

CAS No.

2163056-91-3

SMILES

O=C(N(C)C)CN1N=CC(C2=CC=C(C3=CN=CC4=C3C=CC=C4)C=C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
BI-1347
目录号:
HY-120350
需求量:

BI-1347

Cat. No.: HY-120350