1. Protein Tyrosine Kinase/RTK
  2. c-Fms

c-Fms-IN-1 

目录号: HY-18791
产品使用指南

c-Fms-IN-1 是一种 FMS 激酶抑制剂,IC50 值为 0.0008 μM。

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c-Fms-IN-1 Chemical Structure

c-Fms-IN-1 Chemical Structure

CAS No. : 885703-64-0

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Description

c-Fms-IN-1 is a FMS kinase inhibitor with an IC50 of 0.0008 μM[1].

IC50 & Target

FMS kinase[1]

Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (12.71 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5414 mL 12.7071 mL 25.4143 mL
5 mM 0.5083 mL 2.5414 mL 5.0829 mL
10 mM 0.2541 mL 1.2707 mL 2.5414 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.5 mg/mL (1.27 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.5 mg/mL (1.27 mM); Clear solution

References
Molecular Weight

393.48

Formula

C₂₂H₂₇N₅O₂

CAS No.

885703-64-0

SMILES

CN1CCN(C2=CC=C(NC(C3=CC=C(C#N)O3)=O)C(N4CCCCC4)=C2)CC1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
c-Fms-IN-1
目录号:
HY-18791
需求量:

c-Fms-IN-1

Cat. No.: HY-18791