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CD38 inhibitor 1 

目录号: HY-123999
产品使用指南

CD38 inhibitor 1 是一种有效的 CD38 抑制剂,在人类和小鼠中的 IC50 分别为 7.3 nM 和 1.9 nM。

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CD38 inhibitor 1 Chemical Structure

CD38 inhibitor 1 Chemical Structure

CAS No. : 1700637-55-3

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Description

CD38 inhibitor 1 is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].

In Vivo

CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle[1].

Animal Model: Diet induced obese (DIO) C57Bl6 mice[1]
Dosage: 30 mg/kg
Administration: Orally once
Result: NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

413.53

Formula

C₂₂H₂₇N₃O₃S

CAS No.

1700637-55-3

SMILES

O=C1N(C)C2=C(C=C(C3=CN=CS3)C=C2)C(N[C@H]4CC[C@H](OCCOC)CC4)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
CD38 inhibitor 1
目录号:
HY-123999
需求量:

CD38 inhibitor 1

Cat. No.: HY-123999