1. Anti-infection
  2. Fungal Antibiotic Bacterial
  3. Fluconazole hydrate

Fluconazole hydrate  (Synonyms: 氟康唑水合物; UK 49858 hydrate)

目录号: HY-B0101A
产品使用指南

Fluconazole水合物是抗真菌化合物,可用于表面和全身性的真菌感染。

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Fluconazole hydrate Chemical Structure

Fluconazole hydrate Chemical Structure

CAS No. : 155347-36-7

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  • 生物活性

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生物活性

Fluconazole (hydrate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. Target: Antifungal Fluconazole (hydrate) is the hydrate salt form of fluconazole, which is a triazole antifungal intended for oral treatment of superficial and systemic mycoses. In tests done in standard mycological media, the compound had minimal inhibitory concentrations against pathogenic Candida species that were usually in excess of 100 mg/l. Fluconazole inhibited branching and hyphal development in C. albicans at concentrations as low as 10(-6) M (0.3 mg/l), but miconazole and ketoconazole were still active in these tests at concentrations 100 times lower than this [1]. Oral fluconazole was not associated with a significantly increased risk of birth defects overall or of 14 of the 15 specific birth defects of previous concern. Fluconazole exposure may confer an increased risk of tetralogy of Fallot [2]. Fluconazole is predicted to be ineffective against Cryptococcus gattii in the koala as a sole therapeutic agent administered at 10 mg/kg p.o. every 12 h [3]. Clinical indications: Balanitis; Candida infection; Cryptococcus infection; Cryptococcus neoformans meningitis; Dermatomycosis; Female genital tract infection; Fungal infection; Fungal respiratory tract infection; Fungal urinary tract infection; Prophylaxis; Tinea capitis; Tinea corporis; Tinea cruris; Tinea pedis . Toxicity: Symptoms of overdose include hallucinations and paranoid behavior.

Clinical Trial
分子量

324.29

Formula

C13H14F2N6O2

CAS 号
中文名称

氟康唑水合物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Fluconazole hydrate 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HY-B0101A
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