2. Gene
  3. ABTB2 - ankyrin repeat and BTB domain containing 2 Gene

ABTB2 - ankyrin repeat and BTB domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锚蛋白重复和 BTB 结构域 2

种属: Homo sapiens

同用名: ABTB2A; BTBD22

基因 ID: 25841 | 基因类型: protein coding

关于 ABTB2

This gene has 2 transcripts (splice variants), 257 orthologues and 11 paralogues. Ubiquitous expression in kidney (RPKM 5.3), adrenal (RPKM 5.3) and 24 other tissues.

功能概要

预测可实现蛋白质异二聚化活性。预计在对有毒物质的细胞反应的上游或内部起作用。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein heterodimerization activity. Predicted to act upstream of or within cellular response to toxic substance. [provided by Alliance of Genome Resources, Apr 2022]

ABTB2 基因产物(1)

mRNA Protein Name
NM_145804.3 NP_665803.2 ankyrin repeat and BTB/POZ domain-containing protein 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
36931259 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ABTB2 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (498 - 594)

Ank

Ank: Ankyrin repeat (608 - 633)

BTB

BTB: BTB/POZ domain (838 - 946)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1025 a.a.
蛋白主名 其他名称

ankyrin repeat and BTB/POZ domain-containing protein 2

ankyrin repeat and BTB (POZ) domain containing 2

ABTB2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ABTB2 Q8N961 YWHAE Homo sapiens P62258
Crosslink
36931259
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spermatogenic Failure 15

SPGF15

Spermatogenic Failure, 15
Cardiomyopathy, Dilated, 1e

Left Ventricular Noncompaction 9

Left Ventricular Noncompaction 5

Dilated Cardiomyopathy 1e

Dilated Cardiomyopathy 1s

CMD1E

Cdcd2

Cardiomyopathy, Dilated, 1y

CMD1Y

Cardiomyopathy, Dilated, 1s

CMD1S

Dilated Cardiomyopathy 1y

Dilated Cardiomyopathy With Conduction Defect 2

Dilated Cardiomyopathy With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Defect 2

Cardiomyopathy Dilated With Conduction Defect Type 2

Cardiomyopathy, Dilated 1e

Cardiomyopathy, Dilated 1s

Cardiomyopathy, Dilated 1y

Left Ventricular Non-Compaction 5

LVNC5

Left Ventricular Non-Compaction 9

LVNC9

Cardiomyopathy, Dilated, Type 1e

Cardiomyopathy, Dilated, Type 1s

Cardiomyopathy, Dilated, Type 1y
Megalencephalic Leukoencephalopathy With Subcortical Cysts

Vacuolating Megalencephalic Leukoencephalopathy With Subcortical Cysts

Mlc

Van Der Knaap Disease

Lvm

Leukoencephalopathy With Swelling And Cysts

Megalencephaly-Cystic Leukodystrophy

Megalencephalic Leukodystrophy Megalencephaly-Cystic Leukodystorphy Syndrome

Infantile Leukoencephalopathy And Megalencephaly

Leukoencephalopathy With Swelling And A Discrepantly Mild Course

Vacuolating Leukoencephalopathy

Megalencephalic Leukodystrophy

Megalencephaly-Cystic Leukodystrophy Syndrome

Van Der Knaap Syndrome

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00116 ABTB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS22368 Abtb2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ABTB2 VGNC VGNC:107418
Mus musculus ABTB2 MGD MGI:2139365
Felis catus ABTB2 VGNC VGNC:59495
Rattus norvegicus ABTB2 RGD RGD:620724
Bos taurus ABTB2 VGNC VGNC:25516
Canis familiaris ABTB2 VGNC VGNC:37487
Others ABTB2 NCBI
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