2. Gene
  3. Bag3 - BAG cochaperone 3 Gene

Bag3 - BAG cochaperone 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 293524 | 基因类型: protein coding

关于 Bag3

功能概要

Predicted to enable adenyl-nucleotide exchange factor activity and chaperone binding activity. Involved in several processes, including central nervous system development; chaperone-mediated autophagy; and negative regulation of protein targeting to mitochondrion. Located in neuron projection and stress fiber. Used to study glioblastoma. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Orthologous to human BAG3 (BAG cochaperone 3). [provided by Alliance of Genome Resources, Apr 2022]

Bag3 基因产物(1)

mRNA Protein Name
NM_001011936.1 NP_001011936.1 BAG family molecular chaperone regulator 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
21561597 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
21561597 RGD
involved in negative regulation of protein targeting to mitochondrion IMP
IMP: 通过突变表型推断
21561597 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
19415333 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BAG family molecular chaperone regulator 3

Bcl2-associated athanogene 3

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-117282 JG-98 99.88% 否
HY-156278 FB49 Inhibitor 99.76% 否
HY-170944 BAG3/HSP70-IN-1 / 否
HY-RS01344 BAG3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17327 Bag3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23782 Bag3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Bag3 NCBI NCBI:9531
Mus musculus Bag3 NCBI NCBI:29810
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