2. Gene
  3. LRP3 - LDL receptor related protein 3 Gene

LRP3 - LDL receptor related protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：LDL 受体相关蛋白 3

种属: Homo sapiens

基因 ID: 4037 | 基因类型: protein coding

关于 LRP3

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:33,194,330-33,208,864 (from NCBI)

This gene has 4 transcripts (splice variants), 189 orthologues and 14 paralogues. Ubiquitous expression in ovary (RPKM 23.4), fat (RPKM 17.1) and 24 other tissues.

功能概要

参与脂肪细胞分化的负调控；成骨细胞分化的正调节；和基因表达的调控。预计位于网格蛋白涂层坑中。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Involved in negative regulation of fat cell differentiation; positive regulation of osteoblast differentiation; and regulation of gene expression. Predicted to be located in clathrin-coated pit. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRP3 基因产物(1)

mRNA Protein Name
NM_002333.4 NP_002324.2 low-density lipoprotein receptor-related protein 3 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of fat cell differentiation IMP
IMP: 通过突变表型推断
28340487 GOA
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
28340487 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
28340487 GOA
involved in positive regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
28340487 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

LRP3 蛋白结构

CUB

CUB: CUB domain (43 - 156)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (165 - 200)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (212 - 249)

CUB

CUB: CUB domain (254 - 362)

Ldl_recept_a

Ldl_recept_a: Low-density lipoprotein receptor domain class A (455 - 489)

  • 0
  • 200
  • 400
  • 600
  • 770 a.a.
蛋白主名 其他名称

low-density lipoprotein receptor-related protein 3

105 kDa low-density lipoprotein receptor-related protein

LRP3 抗体

目录号 产品名 应用 反应物种
HY-P83856 LRP3 Antibody (YA3553) WB, ICC/IF, FC, ELISA Human

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103715 NLRP3 modulators 1 Modulator / 否
HY-RS07798 LRP3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17748 Lrp3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24214 Lrp3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus LRP3 VGNC VGNC:68088
Macaca mulatta LRP3 VGNC VGNC:74444
Rattus norvegicus LRP3 RGD RGD:619729
Canis familiaris LRP3 VGNC VGNC:42776
Mus musculus LRP3 MGD MGI:3584516
Bos taurus LRP3 VGNC VGNC:30991
Others LRP3 NCBI
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