1. Gene
  2. PLEKHO1 - pleckstrin homology domain containing O1 Gene

PLEKHO1 - pleckstrin homology domain containing O1 Gene

中文名称:含 O1 的 pleckstrin 同源结构域

种属: Homo sapiens

同用名: JBP; CKIP1; OC120; CKIP-1

基因 ID: 51177 | 基因类型: protein coding

关于 PLEKHO1

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,149,646-150,160,065 (from NCBI)

This gene has 9 transcripts (splice variants), 197 orthologues and 1 paralogue. Broad expression in testis (RPKM 30.7), appendix (RPKM 29.1) and 24 other tissues.

功能概要

预计在几个过程的上游或内部起作用,包括 lamellipodium 形态发生;成肌细胞融合;和成肌细胞迁移。预测定位于细胞投射膜;细胞质;和核。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to act upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Predicted to be located in cell projection membrane; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PLEKHO1 基因产物(4)

mRNA Protein Name
NM_001304722.2 NP_001291651.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304723.2 NP_001291652.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304724.2 NP_001291653.1 pleckstrin homology domain-containing family O member 1 isoform c
NM_016274.6 NP_057358.2 pleckstrin homology domain-containing family O member 1 isoform a
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20580715 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PLEKHO1 蛋白结构

PH

PH: PH domain (24 - 131)

  • 0
  • 100
  • 200
  • 300
  • 409 a.a.
蛋白主名 其他名称

pleckstrin homology domain-containing family O member 1

C-Jun-binding protein

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PLEKHO1 RGD RGD:1311487
Mus musculus PLEKHO1 MGD MGI:1914470
Canis familiaris PLEKHO1 VGNC VGNC:44687
Felis catus PLEKHO1 VGNC VGNC:80309
Bos taurus PLEKHO1 VGNC VGNC:33026
Macaca mulatta PLEKHO1 VGNC VGNC:76101