1. Gene
  2. STOX2 - storkhead box 2 Gene

STOX2 - storkhead box 2 Gene

中文名称:鹳头盒 2

种属: Homo sapiens

基因 ID: 56977 | 基因类型: protein coding

关于 STOX2

Cytogenetic location: 4q35.1 Genomic coordinates (GRCh38): 4:183,798,022-184,023,530 (from NCBI)

This gene has 5 transcripts (splice variants), 278 orthologues and 1 paralogue. Broad expression in brain (RPKM 5.4), thyroid (RPKM 2.4) and 22 other tissues.

功能概要

该基因编码含有 Storkhead-box_winged-helix 结构域的蛋白质。该蛋白在蜕膜组织中差异表达,可能与胎儿生长受限的先兆子痫的易感性有关。交替剪接导致多个转录本变体。[RefSeq 提供,2015 年 9 月]

This gene encodes a Storkhead-box_winged-helix domain containing protein. This protein is differentially expressed in decidual tissue and may be involved in the susceptibility to pre-eclampsia with fetal growth restriction. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

STOX2 基因产物(1)

mRNA Protein Name
NM_020225.3 NP_064610.1 storkhead-box protein 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in embryo development ending in birth or egg hatching IEP
IEP: 通过表达模式推断
20643876 GOA
involved in maternal placenta development IEP
IEP: 通过表达模式推断
20643876 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

STOX2 蛋白结构

Stork_head

Stork_head: Winged helix Storkhead-box1 domain (63 - 142)

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  • 926 a.a.
蛋白主名 其他名称

storkhead-box protein 2

直系同源

种属 基因名 来源 基因 ID
Felis catus STOX2 VGNC VGNC:65797
Canis familiaris STOX2 VGNC VGNC:46934
Rattus norvegicus STOX2 RGD RGD:708477
Macaca mulatta STOX2 VGNC VGNC:78210
Mus musculus STOX2 MGD MGI:1918319
Bos taurus STOX2 VGNC VGNC:35415