2. Vitamin D Related/Nuclear Receptor
  3. Estrogen Receptor/ERR
  4. GW7604

GW7604 是一种抗雌激素药。GW7604 是 GW5638 的代谢物。GW5638 是一种高亲和力的雌激素受体 (ER) 拮抗剂。

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GW7604 Chemical Structure

GW7604 Chemical Structure

CAS No. : 361203-06-7

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规格 价格 是否有货 数量
1 mg ￥2200
In-stock
5 mg ￥5500
In-stock
10 mg ￥8525
In-stock
50 mg   询价  
100 mg   询价  

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GW7604 相关抗体

Top Publications Citing Use of Products

查看 Estrogen Receptor/ERR 亚型特异性产品:

查看所有亚型
Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GW7604 is an antiestrogen. GW7604 is the metabolite of GW5638, which is a high affinity estrogen receptor (ER) antagonist[1].

体外研究
(In Vitro)

GW7604 is the presumed metabolite of GW5638 in breast (MCF-7) and endometrial (ECC-1) cell lines. GW7604 (0.1 nM-1 μM; 24 hours) inhibits both Estradiol (1 nM) and 4-hydroxytamoxifen (4-OHT; 10 and 100 nM) induction of TGF-alpha in a concentration related manner (1-1000 nM) in MDA-MB-231 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

GW7604 相关抗体:

Western Blot Analysis[1]

Cell Line: MDA-MB-231 cells
Concentration: 0.1 nM, 1 nM, 10 nM, 100 nM, 1 μM
Incubation Time: 24 hours
Result: Blocked the effect of estradiol (E2; 1 n M) in a concentration-related manner.
分子量

370.44

Formula

C25H22O3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

COA (170 KB)

产品使用指南 (1538 KB)
参考文献

GW7604 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GW7604361203-06-7GW 7604GW-7604Estrogen Receptor/ERRInhibitorinhibitorinhibit

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Inquiry Information

产品名称：
GW7604
目录号：
HY-117153
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