1. 抗体抑制剂

Inhibitory Antibodies

MCE Inhibitory Antibodies are monoclonal antibodies (mAbs) that have been extensively used in the hottest research areas, such as cancer, immunology and infection. These monoclonal antibodies (mAbs) bind monospecifically to certain cells or proteins, thus stimulating the immune system to attack the malignant tumor cells and preventing tumor growth by blocking specific cell receptors. They can inhibit PD-1, PD-L1, EGFR, VEGFR, TNF-alpha or other targets which are unusually active in diseases, such as non-Hodgkin lymphoma, Hemophilia A, renal cell carcinoma, Parkinson's disease and metastatic HER2-positive breast cancer. For example, by binding to VEGF, Bevacizumab prevents VEGF from interacting with its receptors, thereby inhibiting new vessel growth. Lambrolizumab targets the programmed cell death 1 (PD-1) receptor of lymphocytes. By preventing the binding of its ligands (PD-L1 and PD-L2), Lembrolizumab induces an antitumor immune response.

Inhibitory Antibodies (14):

Cat. No. Product Name Purity Concentration
  • HY-P9907
    Trastuzumab 99.30%
    Trastuzumab 是一种人源化单克隆抗体,其以高亲和力与 HER2 选择性结合。Trastuzumab 已被批准用于治疗 HER2 阳性转移性乳腺癌和 HER2 阳性胃癌。
  • HY-P9906
    Bevacizumab >99.0%
    Bevacizumab 是一种人源化的单克隆抗体,高亲和力且特异性地与所有 VEGF-A 结合。
  • HY-P9903
    Nivolumab 98.54%
    Nivolumab 是一种 PD-1 抗体类抑制剂,用于晚期(转移性)非小细胞肺癌的研究。
  • HY-P9905
    Cetuximab 99.70%
    Cetuximab 是一种单克隆抗体,能够抑制 EGFR,具有抗肿瘤作用。
  • HY-P9904
    Atezolizumab 98.71%
    Atezolizumab 是一种人源化单克隆抗体 IgG1,抵抗程序性死亡因子配体1 (PD-L1),用于癌症研究。
  • HY-P9913
    Rituximab 99.85%
    Rituximab是用于治疗某些自身免疫疾病和癌症类型的抗CD20嵌合单克隆抗体。
  • HY-P9902
    Lambrolizumab 98.56%
    Lambrolizumab 是一种人源化抗体,为 PD-1 的抑制剂,用于癌症免疫的研究。
  • HY-P9908
    Adalimumab 98.12%
    Adalimumab 是一种人源的单克隆 IgG1 抗体,靶向肿瘤坏死因子α (TNF-α)。
  • HY-P9901
    Ipilimumab 99.88%
    Ipilimumab 是一种全人类单克隆抗体 IgG1κ,能够抗 CTLA-4(一种由活化的 T 细胞产生的免疫抑制分子)。
  • HY-P9912
    Pertuzumab 99.10%
    Pertuzumab 是一种人源化单克隆抗体,是一种HER2二聚抑制剂。可用于治疗转移性HER2 阳性乳腺癌。
  • HY-P9911
    Vedolizumab
    Vedolizumab是一种靶向α4β7整联蛋白 (integrin) 的人源化单克隆抗体,用来治疗溃疡性结肠炎和克罗恩病。
  • HY-P9910
    Obinutuzumab
    Obinutuzumab (GA101) 是新型糖工程化II型CD20单克隆抗体,开发用来治疗非霍奇金淋巴瘤。
  • HY-P9909
    Ustekinumab
    Ustekinumab 是一种抗 IL-12/IL-23 的人源单克隆 IgG1κ 抗体。
  • HY-108730
    Avelumab >99.0%
    Avelumab 是一个人 IgG1 抗 PD-L1 单克隆抗体,具有潜在的抗体依赖性细胞介导的细胞毒性作用。