1. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Adrenergic Receptor Endogenous Metabolite
  3. Methyldopa hydrochloride

Methyldopa hydrochloride  (Synonyms: 盐酸甲基多巴; L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride)

目录号: HY-B0225A
产品使用指南

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) 是一种 α-肾上腺素能激动剂(对 α2-adrenergic receptors 有选择性)。Methyldopa hydrochloride 是一种前体,在中枢神经系统中被代谢 (α-Methylepinephrine)。

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Methyldopa hydrochloride Chemical Structure

Methyldopa hydrochloride Chemical Structure

CAS No. : 884-39-9

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Methyldopa hydrochloride 的其他形式现货产品:

Other Forms of Methyldopa hydrochloride:

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  • 生物活性

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生物活性

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

IC50 & Target

α adrenergic receptor

 

体内研究
(In Vivo)

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 60-day-old male rats[2]
Dosage: 200 mg/kg
Administration: I.p.
Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Clinical Trial
分子量

247.68

Formula

C10H14ClNO4

CAS 号
中文名称

盐酸甲基多巴; 盐酸卡比多巴EP杂质A

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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