1. 多肽产品
  2. 多肽及其衍生物
  3. 抑制剂与底物肽
  4. NG2 binding peptide

NG2 binding peptide 是特异性识别 NG2 蛋白多糖的短肽,可通过噬菌体筛选技术得到。NG2 binding peptide 通过与 NG2 结合位点相互作用,在体外和体内实现对肿瘤新生血管的精准靶向。NG2 binding peptide 在野生型荷瘤小鼠中展现出显著的归巢能力,而在 NG2 基因敲除小鼠中则无定位效果。由于 NG2 表达的组织特异性,NG2 binding peptide 可被用于肿瘤靶向治疗、药物递送及分子影像诊断等场景。

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Custom Peptide Synthesis

NG2 binding peptide Chemical Structure

NG2 binding peptide Chemical Structure

CAS No. : 241478-23-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NG2 binding peptide is a short peptide that specifically recognizes NG2 proteoglycan and can be obtained by phage screening technology. NG2 binding peptide interacts with NG2 binding sites to achieve precise targeting of tumor angiogenesis in vitro and in vivo. NG2 binding peptide exhibits significant homing ability in wild-type tumor-bearing mice, but has no localization effect in NG2 knockout mice. Due to the tissue specificity of NG2 expression, NG2 binding peptide can be used in scenarios such as tumor targeted therapy, drug delivery, and molecular imaging diagnosis[1].

分子量

1016.13

Formula

C40H69N15O14S

CAS 号
Sequence

Thr-Ala-Ala-Ser-Gly-Val-Arg-Ser-Met-His

Sequence Shortening

TAASGVRSMH

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NG2 binding peptide
目录号:
HY-P10989
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